. Author manuscript; available in PMC: 2019 Oct 1.

Published in final edited form as: Mult Scler Relat Disord. 2018 Jul 12;25:29–36. doi: 10.1016/j.msard.2018.06.007

Table 4.

Between-group comparison of cortical activation maps (p<0.05, cluster corrected for multiple comparisons).

Comparison	Regions	Side	BA	MNI coordinates (x,y,z)	Cluster Size	Max z
AAs > CTRLs	IPL	L	40	−64, −34, 34	525	3.56
AAs > CTRLs	Insula	R	13	42, −2, −8	516	3.13
CAs > CTRLs	SFG	L	6	−24, −2, 68	1515	3.27
CAs > CTRLs	PC	L	7	−22, −64, 54	722	3.41
AAs < CAs	MedFG	L	9	−8, 52, 34	799	−4.22

Anatomical coordinates in the standard MNI space, maximum z-values and cluster size for clusters showing significantly different activation in patient subgroups vs CTRLs and in AAs vs CAs (two-sample t-test, FEW-corrected for multiple comparisons at cluster level, p<0.05). Abbreviations: AAs=African-Americans, BA=Brodmann area, CAs=Caucasians, CTRLs=controls, IPL=inferior parietal lobule, L=left, MedFG=medial frontal gyrus, PC=precuneus, , R=right, SFG=superior frontal gyrus.