Fig. 3.

Top three discriminative features identified within the modeling set (1 = Orientation: range tensor information_measure1_a = 0.42; 2 = Orientation:range tensor information_measure1_a = 0.43; 3 = Orientation:standard deviation tensor information_measure1_a = 0.42). They are entropy-related measurement capering the degree of disorder of nuclear orientation locally (for more feature explanation please refer to the Supplementary Materials Appendix). Higher feature values reflect more disorder in orientations of adjacent nuclei. The p values were calculated via the paired Student’s t test