Skip to main content
. Author manuscript; available in PMC: 2019 Feb 24.
Published in final edited form as: Lab Invest. 2018 Aug 24;98(11):1465–1477. doi: 10.1038/s41374-018-0101-0

Figure 10.

Figure 10

The expression of (A) collagen type-1a, (B) TGF-β1 and (C) fibronectin-1 were increased in hHSCs treated with cholangiocyte supernatant from Mdr2−/− mice fed BAC compared to basal and WT supernatant treatments; however, expression of these fibrotic markers were decreased when hHSCs were stimulated with cholangiocyte supernatants from Mdr2−/− mice fed UDCA. Data are expressed as mean ± SEM of at least 6 experiments for real-time PCR. *p<0.05 versus WT mice; #p<0.05 versus Mdr2−/− mice fed BAC.