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. Author manuscript; available in PMC: 2019 Feb 24.
Published in final edited form as: Lab Invest. 2018 Aug 24;98(11):1465–1477. doi: 10.1038/s41374-018-0101-0

Figure 5.

Figure 5

(A) Staining for Masson’s Trichrome and (B) Fast Green/Sirius Red demonstrate an increase in collagen content in Mdr2−/− mice fed BAC compared to WT. UDCA feeding decreased collagen content as shown by semi-quantification of Fast Green/Sirius Red staining (B). (C) Qualitative expression of SYP-9 (green staining) increased in Mdr2−/− mice fed BAC compared to WT; whereas, treatment with UDCA decreased qualitative SYP-9 expression (bile ducts are depicted by red staining). Data are expressed as mean ± SEM of at least 9 experiments. *p<0.05 versus WT mice; #p<0.05 versus Mdr2−/− mice fed BAC diet. Images are 40× magnification.