Figure 5.
MALAT-1 knockdown mimics the effect of miR-182-5p overexpression. A Relative expression of MALAT-1 after transient transfection with MALAT-1 anti-sense oligonucleotide. B Proliferation of Caki-1 and ACHN after anti-MALAT-1 transfection was significantly reduced compared to control. C Anti-MALAT-1 significantly reduces the colony forming ability of both Caki-1 and ACHN. D MALAT-1 knockdown leads to G2/M arrest in both the cell lines. P-value calculated by Student t-test. Bar = mean± SE.