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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Mol Cancer Res. 2018 Jul 23;16(11):1750–1760. doi: 10.1158/1541-7786.MCR-17-0762

Figure 6.

Figure 6

miR-182-5p over-expression associated with mitotic progression of the cell cycle. A Heatmap generated from 84 key genes involved in cancer related pathways display the fold cahge for each gene in both Caki-1 and ACHN cells transfected with miR182-5p. Column represent individual cell line and each row represents individual assayed gene. Green represents downregulation of the gene and, red represents upregulation of gene . B qPCR analyses for some of the altered genes after miR-182-5p transfection in both Caki-1 and ACHN cells. C Decreased expression of AURKA and CDC20 in Caki-1 and ACHN cells after MALAT-1 ASO transfection at mRNA level. D Confirmation of decreased expression of AURKA and CDC20 at protein level in Caki-1 and ACHN cells after transfection with miR-182-5p mimic and MALAT-1 ASO transfection compared with respective controls. P-value calculated by Student t-test. Bar = mean± SE.