Table 3.
Secondary Outcomes and Mediating Variables
| Domain | Measure | Timepointa |
|---|---|---|
| Threat Beliefs | Risk Behavior Diagnosis Scale[133, 134] perceived susceptibility and severity of HBOC subscales | T1, T2, T3, T4 |
| Efficacy Beliefs | Risk Behavior Diagnosis Scale[133, 134] self-efficacy and response efficacy regarding genetic counseling subscales | T1, T2, T3, T4 |
| Fear | Fear of HBOC risk (self, family): Affect in Risk Scale[135–137] | T1, T2, T3 |
| Defensive Avoidance | Defensive Avoidance[35, 138] | T1, T2, T3 |
| Distress, Stress and Worry | Cancer Worry Scale; [139, 140] Psychological distress: anxiety and depression subscales of the Brief Symptom Inventory;[141–143] Short Perceived Stress Scale[144, 145] | T1, T2, T3, T4 |
| Decisional Regret and Satisfaction about genetic counseling and testing decisions | SURE Scale[146, 147]; Decision Satisfaction Scale[148, 149] and original contributions | T1, T2, T3, T4 |
| Genomics and HBOC Knowledge | Items from the National Center for Human Genome Research Knowledge Scale and additional items specific to breast and ovarian cancer survivors[150, 151]; Original contributions assess whether participants heard about or were referred for CGRA and HBOC genetic testing (e.g., BRCA1/2) prior to being contacted for this study | T1, T2 |
| Genetic Self Efficacy | Items assess confidence in their ability to understand genetic information and how it applies to personal health[152–154] | T1, T2 |
| Belief that the GINA law would adequately protect against genetic based discrimination | Genetic Information Non-Discrimination Act (GINA) Law Confidence Scale[155] | T1, T2 |
| Facilitators and Barriers Regarding CGRA | Facilitators and Barriers to genetic counseling and testing at the individual, interpersonal, structural and system-level are assessed[23, 101, 105, 108] | T1, T2, T3, T4 |
T1 = baseline; T2 = 1 month after baseline for UC or 1 month following TP or TCN; T3 = 6 months after baseline for UC or 6 months following TP or TCN; T4 = 12 months after baseline for UC or 12 months from TP or TCN