Table I.
Donor screening tests for blood-borne viruses.
| Test | Recommended | Mandatory* |
|---|---|---|
| Anti-HIV | Yes | Yes |
| Anti-HCV | Yes | Yes |
| HbsAg (HBV) | Yes | Yes |
| HIV-RNA (NAT) | Yes | No |
| HCV-RNA (NAT) | Yes | No |
| HBV-DNA | Yes | No |
| Parvovirus B19 DNA | Yes | No |
| HAV RNA | Yes | No |
*
While nucleic acid testing (NAT) is not mandatory in many countries, it represents the best blood safety practice and is mandatory in some well-regulated countries (e.g., the US Food and Drug Administration).
DNA: deoxyribonucleic acid; HBV: hepatitis B virus; HbsAg: antigen associated with HBV; HCV: hepatitis C virus; HIV: human immunodeficiency virus; RNA: ribonucleic acid; HAV: hepatitis A virus.