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. 2018 Nov 2;9:4600. doi: 10.1038/s41467-018-06833-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — MYH10 is upregulated in emphysematous human lungs. a Representative western blot for human MYH10 of lung tissues from healthy donors (three individuals) and emphysema patients (four individuals). b Quantification of MYH10 expression of lung tissues from healthy donors (three individuals) and emphysema patients (four individuals). c Immunostaining for MYH10 and NKX2-1 in adult human lungs. d Immunostaining for MYH10 and α-SMA in adult human lungs. pa, pulmonary artery. e Immunostaining for MYH10 in healthy control and emphysema patient lungs. Arrowheads point to smooth muscle cells. L left, R right. Error bars are means ± s.e.m. **P < 0.01, two-tailed Student’s t-test. Scale bars: 100 μm (e (top)), 50 μm (c, d), 30 μm (e (bottom))