Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 2;8:16241. doi: 10.1038/s41598-018-34263-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Effect of HD5 feeding on EtOH-induced down regulation of α-defensin, cytokine and chemokine gene expression in mouse ileum. Adult mice were subjected to DSS-induced colitis three times with 15-day intervals, followed by 30-day recovery from third colitis. During the intervals and recovery period, mice were fed a liquid diet with EtOH (EF) or isocaloric maltodextrin (PF) and with or without HD5 supplementation. (A–C) RNA extracted from ileal mucosa was subjected to RT-qPCR for Defa4 (A), Defa5 (B) and Defa6 (C) genes. (D–J) RNA extracted from mucosa of ileum was subjected to qPCR for IL-1β (D), TNFα (E), IL-6 (F), CCL5 (G), MCP1 (H), IL-10 (I) and TGFβ (J) genes. Values in all panels are mean ± sem (n = 6). Asterisks indicate the values that are significantly (p < 0.05) different from corresponding PF values, and the hash tags indicate the values significantly different from corresponding values for DSS without EtOH group. The symbol Δ indicates values that are different from corresponding values for DSS + EF group.