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. 2018 Nov 2;8:240. doi: 10.1038/s41398-018-0292-6

Table 4.

Contrast analysis for pain i.e., Noxious Heat (PTSD: 46 °C–PTSD: 42 °C)–Control: 46 °C–Control: 42 °C)

Brain region Lat. Zstat x y z cm3
Positive
Cortical
Frontal
Middle R 4.5149 4 52 −12 6.216
Superior L 3.3138 −14 50 34 2.912
Middle_Orbital R 4.1583 28 48 22 5.256
Inferior_Triangular R 3.088 50 46 −2 4.576
Superior_Medial L 4.4573 −10 44 44 5.184
Middle R 3.6398 6 44 −2 2.672
Inferior_Orbital L 4.2308 −50 44 −8 6.816
Superior_Medial L 3.2365 −8 42 24 1.888
Middle_Orbital L 3.6153 −6 42 −14 0.88
Inferior_Orbital L 3.3324 −34 38 −18 9.248
Rectus L 3.8512 2 36 −24 4.568
Middle L 3.0899 −30 34 42 2.344
Superior_Medial L 3.6588 −6 32 40 2.976
Middle_Orbital R 3.1365 40 32 22 11.888
Inferior_Triangular L 3.2889 −50 32 14 3.848
Inferior_Orbital R 3.6127 28 30 −24 2.392
Superior_Orbital R 3.8527 14 28 52 3.488
Middle L 3.1438 −50 20 40 2.84
Supp_Motor_Area L 4.8875 −2 18 50 32.792
Precentral L 3.1636 −46 2 40 9.48
Precentral L 3.6611 −38 −16 58 9.592
Precentral R 3.2171 32 −20 58 4.032
Parietal
Angular R 3.1444 48 −50 30 4.584
Inferior L 3.7698 −54 −56 36 4.592
Angular R 3.4722 46 −60 30 2.368
Angular R 3.3966 44 −62 26 2.136
Angular L 3.9151 −52 −62 26 3.192
Occipital
Rolandic_Operculum L 3.1518 −54 10 0 5.248
Temporal
Middle L 3.0839 −50 4 −22 1.664
Middle L 4.1141 −42 2 −30 6.616
Inferior L 3.1285 −38 −24 −30 10.24
Inferior R 3.8777 48 −48 −8 6.768
Middle L 3.4588 −44 −52 16 6.072
Inferior R 3.2829 54 −52 −8 1.856
Middle L 3.5635 −56 −60 −4 8.112
Inferior R 3.7377 58 −60 −18 6.792
Cingulum
Anterior L 3.648 −6 42 8 6.88
Anterior L 3.2944 −6 30 24 1.432
Anterior L 4.1817 −6 22 22 5.728
Post L 3.6965 −6 −48 28 8.08
Insula
Insula_Anterior R 3.1325 30 22 −16 1.992
Insula_Anterior R 3.1263 36 4 16 3.96
Sub-Cortical
Putamen R 3.5437 26 14 0 4.256
Caudate L 3.2604 −12 14 0 0.712
NAc L 3.9158 −10 8 −6 4.928
Pallidum L 3.4741 −14 2 −2 2.168
Amygdala R 3.7746 32 −6 −12 5.96
Pallidum R 3.9179 28 −14 −2 5.952
Hippocampus L 3.7027 −22 −16 −16 7.408
Brainstem/Cerebellum
PAG 3.179 −2 −26 −6 3.456
Cerebellum_8 L 3.1324 −22 −38 −50 1.432
Cerebellum_6 R 6.2048 36 −46 −26 21.496
Cerebellum_Crus2 L 3.5623 −42 −56 −42 5.088
Cerebellum_8 R 3.6938 34 −56 −54 7.368
Vermis_4_5 3.1742 0 −60 −10 7.072
Cerebellum_6 R 3.3647 14 −60 −20 2.216
Cerebellum_Crus1 L 4.0219 −32 −62 −34 2.904
Cerebellum_Crus1 L 4.0019 −36 −62 −34 1.92
Cerebellum_6 L 3.717 −36 −62 −24 3.816
Cerebellum_Crus1 R 3.7558 52 −64 −32 2.8
Negative
Cortical
Frontal
Inferior_Orbital L 2.1532 −30 34 −6 1.416
Rectus L 2.9197 −6 26 −18 1.32
Middle_Orbital R 2.0634 30 18 40 1.104
Precentral L 1.9161 −36 0 30 0.336
Paracentral_Lobule R 2.2028 8 −30 64 0.824
Parietal
Postcentral L 2.1779 −58 −10 40 0.816
Postcentral R 2.4261 48 −18 40 1.344
Postcentral R 2.7418 34 −30 40 1.192
Fusiform R 2.0777 24 −30 −20 1.504
Postcentral R 2.9956 22 −36 80 2.152
Postcentral L 2.0547 −26 −40 78 1.624
Precuneus L 2.0737 −16 −42 68 1.024
Precuneus L 2.1096 −8 −44 78 0.424
Precuneus R 2.3315 26 −50 2 0.968
Superior R 2.0322 22 −50 70 0.424
Inferior L 1.8085 −32 −52 48 0.256
Occipital
Middle L 2.1494 −28 −60 32 1.432
Temporal
Superior R 2.0631 62 2 −2 0.664
Superior R 1.9796 66 −14 10 0.424
Superior L 1.9296 −66 −26 6 0.456
Superior R 2.3064 44 −42 4 1.152
Superior R 1.856 62 −44 20 0.448
Lingual R 2.0713 16 −46 −6 0.752
Middle R 2.6184 64 −52 10 1.92
Cingulum
Middle R 2.8207 14 10 42 3.448
Middle R 2.7638 12 −20 46 1.92
 Insula
Insula_Posterior L 2.2091 −46 −10 4 0.616
Sub-Cortical
Amygdala L 2.2135 −24 −2 −22 0.48
Hypothalamus R 2.2421 4 −4 −14 0.616
 Brainstem/Cerebellum
Cerebellum_Crus2 L 2.742 −52 −44 −42 1.112
Cerebellum_4_5 L 1.788 −8 −44 −4 0.232
Cerebellum_9 L 1.7861 −12 −52 −42 0.216