Table 4.
Gender related outcomes.
| Variable | Female | Male | P-value |
|---|---|---|---|
| Age | 8.53 | 8.20 | 0.89 |
| WBC | 116.7 | 156.1 | 0.61 |
| CNS3 (+/-) | 3/9 | 12/39 | 0.91 |
| Induction death (+/-) | 2/10 | 1/50 | 0.031 |
| Post-induction death (+/-) | 3/7 | 4/46 | 0.048 |
| Relapse (+/-) | 3/7 | 3/47 | 0.021 |
| Protocol | |||
| - C-MTX (+/-) | 6/6 | 21/30 | 0.56 |
| - HDMTX (+/-) | 6/6 | 30/21 | 0.58 |
| 5-year OS | 64.3 ± 17% | 91.9 ± 3.4% | 0.043 |
| 5-year DFS | 56. ± 17% | 90 ± 4.3% | 0.011 |
| 5-year DFS – C-MTX | 25 ± 22% | 95.2 ± 4.7% | <0.0001 |
| 5-year DFS – HDMTX | 83. ± 15.2% | 86 ± 6.4% | 0.86 |
(+/-) = (# with characteristic/# without characteristic).