. 2018 Oct;70:15–24. doi: 10.1016/j.placenta.2018.08.006

Table 1.

Temporal Changes in both Placental and Endometrial mRNA Expression were observed.

Gene	GD18	GD30	GD45	GD60	GD90	P Value
Relative Placental mRNA Expression (Mean ± S.E.M.)
BAX	n/a	1.563 ± 0.186^a	2.891 ± 0.116 ^b	2.149 ± 0.202^c	2.764 ± 0.193 ^b	P ≤ 0.001
BCL2	n/a	6.495 ± 1.198^a	22.071 ± 3.254^bc	15.305 ± 2.609^bd	26.433 ± 4.539^b	P ≤ 0.001
BAX:BCL2 Ratio	n/a	0.327 ± 0.068	0.190 ± 0.026	0.178 ± 0.015	0.189 ± 0.039	ns
P53	n/a	2.126 ± 0.169^a	3.908 ± 0.145^b	3.213 ± 0.229^bc	3.081 ± 0.282^c	P ≤ 0.01
KI67	n/a	2.134 ± 0.182^ab	2.700 ± 0.140^a	1.945 ± 0.180^b	2.207 ± 0.206^ab	P ≤ 0.05
Relative Endometrial mRNA Expression (Mean ± S.E.M.)
BAX	4.079 ± 0.634	4.298 ± 0.217	4.665 ± 0.446	3.812 ± 0.385	3.450 ± 0.863	ns
BCL2	6.639 ± 0.640^a	2.930 ± 0.379^b	3.569 ± 0.460^b	3.630 ± 0.419^b	2.592 ± 0.871^b	P ≤ 0.001
BAX:BCL2 Ratio	0.636 ± 0.093^a	1.670 ± 0.197^b	1.506 ± 0.156^b	1.141 ± 0.110^ab	1.354 ± 0.922^b	P ≤ 0.05
P53	6.511 ± 0.727^a	4.888 ± 0.560^ab	4.069 ± 0.411^b	4.161 ± 0.396^b	3.268 ± 0.869^b	P ≤ 0.01
KI67	2.408 ± 0.257	2.654 ± 0.226	2.264 ± 0.211	2.335 ± 0.190	1.958 ± 0.898	ns

P value indicates overall temporal change detected by ANOVA with a block for gilt or Kruskal-Wallis. Differing superscript letters indicate that group means differ from one another. n = 10–23 samples per group. ns=not significant.