Table 3.
The content of major neurotransmitters and their metabolites in the hippocampus
| Compound | Virgin | Parous | ||
|---|---|---|---|---|
| Control | Supplementary | Control | Supplementary | |
| DA (ng/g) | 6.3 ± 0.8 | 5.0 ± 0.7 | 4.2 ± 0.4# | 3.6 ± 0.5# |
| DOPAC (ng/g) | 3.1 ± 0.5 | 2.0 ± 0.2 | 3.1 ± 0.7 | 3.5 ± 0.7 |
| HVA (ng/g) | 0.5 ± 0.1 | 0.4 ± 0.1 | 0.3 ± 0.0 | 0.4 ± 0.1 |
| NE (ng/g) | 3.8 ± 0.4 | 3.5 ± 0.5 | 2.7 ± 0.3 | 3.0 ± 0.3 |
| MHPG (ng/g) | 0.4 ± 0.0 | 0.3 ± 0.0 | 0.3 ± 0.0 | 0.3 ± 0.0 |
| VMA(ng/g) | 4.0 ± 0.3 | 3.5 ± 0.7 | 4.5 ± 0.4 | 3.5 ± 0.4 |
| TRY (ug/g) | 4.8 ± 0.3 | 4.0 ± 0.1 | 3.7 ± 0.1 | 4.6 ± 0.4 |
| 5-HT (ng/g) | 129.6 ± 17.9 | 105.5 ± 14.0 | 108.1 ± 9.1 | 121.1 ± 12.3 |
| 5-HIAA (ng/g) | 194.5 ± 30.3 | 166.8 ± 29.6 | 123.4 ± 9.5 | 71.8 ± 14.1## |
| 5-HIAA/5-HT | 1.8 ± 0.5 | 2.3 ± 0.6 | 0.7 ± 0.1 | 0.7 ± 0.2# |
| KYN (ng/g) | 282.6 ± 24.5 | 242.4 ± 6.9 | 222.8 ± 8.8 | 239.3 ± 14.4 |
| GABA (ug/g) | 63.3 ± 5.0 | 49.5 ± 3.1 | 31.6 ± 1.5## | 34.4 ± 1.5 |
| GLU (ug/g) | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.1 ± 0.0 |
| GLN (ug/g) | 48.3 ± 3.7 | 38.0 ± 3.7 | 29.2 ± 1.3## | 32.5 ± 1.1 |
Data are means ± SEM (n = 6–7). #p < 0.05, ##p < 0.01 compared to virgin group; *p < 0.05, **p < 0.01compared to control group