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. 2018 Oct 25;11(10):dmm034611. doi: 10.1242/dmm.034611

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© 2018. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 4. — Localization of the SIX4 and SIX5 proteins in the PAW. (A-F) SIX4 and SIX5 proteins localize in surface ectodermal cells, CECs (arrow) and mesenchymal cells in the PAW at E10.0 (A-C) and E10.25 (D-F). (G-I) SIX5 but not SIX4 is detected in the PAW at E11.5. Insets in G-I indicate the localization of SIX4 and SIX5 in the dorsal root ganglia. Dotted lines indicate inner and outer surfaces of the PAW. (J) Illustration of localization patterns of SIX4 and SIX5 at E10.0, E10.25 and E11.5. DRG, dorsal root ganglia; e, ectoderm; M, muscle progenitors; S, somite; SC, spinal cord. Scale bars: 50 μm in A-I; 25 μm in inset of G-I.