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. 2018 Sep 27;5(11):ofy245. doi: 10.1093/ofid/ofy245

Table 3.

Independent Predictors for Individual DFI-PRRT

PAb vs Non-PA, OR (95% CI)
(n = 94)
VREc vs Non-VRE, OR (95% CI)
(n = 52)
3GCE-REd vs Non-3GCE-RE, OR (95% CI)
(n = 51)
Recent hospitalization 1.50
(0.91–2.46)
3.37
(1.66–6.84)
1.00
(0.46–2.21)
Residence of LTCF 1.11
(0.51–2.41)
a 3.85
(1.58–9.39)
Peripheral vascular disease 1.68
(0.95–2.96)
17.51
(2.37–129.21)
3.45
(1.29–9.25)
Congestive heart failure a a 1.31
(0.68–2.52)
Dementia a a 1.70
(0.68–4.27)
Dependent status (bedridden) 1.74
(0.98–3.09)
a 1.21
(0.51–2.86)
Prior debridement a 0.97
(0.51–1.86)
a
History of diabetic foot ulcer associated with PA 3.06
(1.14–8.20)
a a
History of diabetic foot ulcer associated with VRE a 7.83
(1.82–33.64)
a
History of diabetic foot ulcer associated with 3GCE-RE a a 8.95
(0.76–105.60)
Prior BLBLI use a a 2.69
(1.18–6.15)
Prior cephalosporin, third generation a a 2.95
(1.11–7.88)
Prior cefepime use 2.41
(1.09–5.34)
a 3.27
(1.27–8.40)
Prior vancomycin use a 1.67
(0.83–3.37)
a

Abbreviations: 3GCE-RE, third-generation cephalosporin-resistant Enterobacteriaceae; BLBLI, beta-lactam/beta-lactamase inhibitor; DFI, diabetic foot infection; LTCF, long-term care facility; NS, nonsignificant; PA, Pseudomonas aeruginosa; PRRT, pathogens resistant to empiric recommended treatment; VRE, vancomycin-resistant Enterococcus spp.

aVariables were not included in the model.

bControlled for LTCF, dependent status, recent hospitalization, chronic kidney disease, peripheral vascular disease, prior quinolone use, history of PA in a diabetic foot ulcer, and prior use of cefepime.

cControlled for LTCF, chronic kidney disease, prior debridement, and prior vancomycin use.

dControlled for dependent status, recent hospitalization, congestive heart failure, dementia, and history of 3GCE-RE in a diabetic foot ulcer.