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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: J Pain. 2018 May 25;19(11):1285–1295. doi: 10.1016/j.jpain.2018.05.005

Figure 3. C57BL/6 Sub-strains Have Different Intrinsic Activity and Energy Expenditure on a High Fat Diet.

Figure 3

A) Control-fed and high fat-fed C57BL/6J mice display significantly greater activity during dark cycle than C57BL/6CR or C57BL/6NJ mice (n=8 for all groups). B) No sub-strain or diet group displayed an alteration in energy intake during active dark cycle time. C) All high fat-fed substrains displayed a reduced respiratory quotient associated with increased fat fuel utilization during their active dark cycle. D) Control-fed C57BL/6CR showed reduced energy expenditure relative to high fat-fed C57BL/6CR and control-fed C57BL/6J and C57BL/6NJ animals. All data presented as mean ± SEM * p<0.05; ** p<0.01; *** p<0.001; **** p<0.0001 CF: Control-fed HF: High fat-fed