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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Mol Cancer Ther. 2018 Sep 11;17(11):2481–2489. doi: 10.1158/1535-7163.MCT-18-0156

Table1. Production of SDR rats by implanting Rag2 SSCs into sterile males.

Four recipient males were transplanted with genetically modified SSCs. Only one recipient (526300) had no surgical complications and had good fill of testis with modified SSCs. Only that recipient produced pups when mated with wild type females.

Animal
ID		 Time from
thaw to
transplant		 Right
testis (fill %)		 Left
Testis (fill %)		 Surgery
outcome		 Days to
mating		 Days to
1st litter		 Total
pups
screened		 Rag2
pups
526308 0.75 h 20 10 Good 77 n/a n/a n/a
526300 1.6 h 15 90 Good 81 142 60 1
526309 2 h 60 100 Survived, but
was bleeding
during surgery		 70 n/a n/a n/a
526310 2.75 h Miss 75 Survived, but
was bleeding
during surgery		 70 n/a n/a n/a