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Small molecule inhibitor, PKC412, modulates the expression of Myc network genes in human MV4-11 cells. The human Flt3-ITD mutated leukemia cell line, MV4-11, was treated with the Flt3-inhibitor PKC412 at two different concentrations (0.1 mM and 1 mM) for 15 minutes. Expression analysis of the Myc network genes was carried out with RT-Q-PCR. ND: not detected.
