Table 1.
Shown are the results of univariable binary logistic regression to determine the influence of each preoperative variable on 10-year survival after liver resection. Odds ratios greater than 1 with a significant p value (p<0.05) indicate variables that increase the risk of mortality within 10 years significantly whereas odds ratios smaller than 1 with a significant p value indicate variables that decrease the risk of mortality within 10 years.
| Variables | Odds Ratio | 95%-Confidence interval | p-value | ||
|---|---|---|---|---|---|
| Pre-operative variables | Female gender (yes/no) | 0.986 | 0.687 – 1.416 | 0.941 | |
| Male gender (yes/no) | 1.014 | 0.706 – 1.455 | 0.941 | ||
| Age at operation of primary tumor (years) | 1.029 | 1.013 – 1.046 | <0.001 | ||
| Age at liver resection (years) | 1.028 | 1.012 – 1.045 | <0.001 | ||
| Time between resection of primary tumor and resection of metastases (days) | 1.000 | 0.999 – 1.000 | 0.900 | ||
| Localization of primary tumor | Coecum (yes/no) | 2.119 | 0.902 – 4.980 | 0.058 | |
| Colon ascendens (Yes/no) | 0.895 | 0.528 – 1.517 | 0.683 | ||
| Colon transversum (yes/no) | 1.061 | 0.438 – 2.570 | 0.895 | ||
| Colon descendens (yes/no) | 1.136 | 0.568 – 2.269 | 0.715 | ||
| Colon sigmoideum (yes/no) | 0.659 | 0.462 – 0.941 | 0.023 | ||
| Rectum (yes/no) | 1.314 | 0.891 – 1.939 | 0.162 | ||
| Stage and grading of primary tumor | pT1-4 (ordinal scale) | not determined | 0.004 | ||
| pT1 vs. pT2 | 0.965 | 0.375 – 2.478 | 0.940 | ||
| pT1 vs. pT3 | 0.610 | 0.255 – 1.454 | 0.264 | ||
| pT1 vs. pT4 | 0.214 | 0.069 – 0.670 | 0.008 | ||
| pN0-2b (ordinal scale) | not determined | 0.034 | |||
| pN0 vs. pN1 | 0.587 | 0.380 – 0.906 | 0.016 | ||
| pN0 vs. pN2a | 0.551 | 0.335 – 0.907 | 0.019 | ||
| pN0 vs. pN2b | 0.912 | 0.385 – 2.158 | 0.834 | ||
| M1 (yes/no) | 1.489 | 1.017 – 2.181 | 0.038 | ||
| Grading G1-3 (ordinal scale) | not determined | 0.012 | |||
| Grading G1 vs. G2 | 0.324 | 0.140 – 0.750 | 0.009 | ||
| Grading G1 vs. G3 | 0.162 | 0.054 – 0.481 | 0.001 | ||
| UICC I-IV (ordinal scale) | not determined | 0.016 | |||
| UICC I vs. IIa | 0.438 | 0.227 – 0.844 | 0.014 | ||
| UICC I vs. IIb | 0.206 | 0.025 – 1.687 | 0.141 | ||
| UICC I vs. IIIa | 0.452 | 0.166 – 1.235 | 0.122 | ||
| UICC I vs. IIIb | 0.312 | 0.154 – 0.633 | 0.001 | ||
| UICC I vs. IIIc | 0.422 | 0.207 – 0.862 | 0.018 | ||
| UICC I vs. IV | 0.318 | 0.178 – 0.567 | <0.001 | ||
| Chemotherapy of primary tumor (yes/no) | 1.831 | 1.281 – 2.618 | <0.001 | ||
| Radiotherapy of primary tumor (yes/no) | 1.847 | 0.991 – 3.444 | 0.039 | ||
| Local recurrence of primary tumor (yes/no) | 1.229 | 0.617 – 2.447 | 0.549 | ||
| Simultaneous resection of primary tumor and liver metastases (yes/no) | 0.979 | 0.502 – 1.909 | 0.950 | ||
| Multiple resection of metastases (yes/no) | 1.131 | 0.624 – 2.048 | 0.682 | ||
| Leukocytes Tsd/μl | 1.035 | 0.954 – 1.124 | 0.397 | ||
| Platelets Tsd/μl | 0.999 | 0.997 – 1.000 | 0.155 | ||
| Hemoglobin g/dl | 0.891 | 0.789 – 1.007 | 0.062 | ||
| Quick's value % | 0.979 | 0.966 - 0.992 | 0.002 | ||