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. 2018 Oct 21;2018:5156710. doi: 10.1155/2018/5156710

Table 4.

Body and organ weights of rats subjected to subacute toxicity assessment of the hydroethanolic extracts of E. floribundus and A. indica.

Groups Body weight (g) ± SD
Day 0 Day 7 Day 14 Day 21 Day 28
(A) Rats treated with HEEF
Control 123.3±9.1 127.8±8.8 131.8±9.2 136.8±8.8 143.5±9.5
60 mg/kg 123.3 ± 10.3 126.3 ± 9.7 129.8 ± 9.6 131.8 ± 9.9 134.7±10.2
120 mg/kg 123.3 ± 8.8 126.3 ± 9.0 129.7 ± 11.5 130.3 ± 8.2 133.0±7.7
240 mg/kg 123.0 ± 13.1 126.4 ± 12.5 130.4 ± 8.6 132.0±10.7 134.2±10.6

Groups Organ weight (g) ± SD
Liver Heart Kidneys Lungs Spleen

Control 5.72 ± 0.66 0.62 ± 0.05 1.28 ± 0.13 1.16 ± 0.11 0.78 ± 0.19
60 mg/kg 5.15 ± 0.58 0.60 ± 0.08 1.26 ± 0.13 1.51 ± 0.65 0.80 ± 0.14
120 mg/kg 4.54 ± 1.46 0.54 ± 0.05 1.21 ± 0.09 1.39 ± 0.36 0.70 ± 0.15
240 mg/kg 5.16 ± 0.32 0.52 ± 0.06 1.17 ± 0.04 1.40 ± 0.53 0.79 ± 0.19

Groups Body weight (g) ± SD
Day 0 Day 7 Day 14 Day 21 Day 28

(B) Rats treated with HEAI
Control 123.3 ± 9.11 127.8 ± 8.8 131.8 ± 9.2 136.8 ± 8.8 143.5 ± 9.5
75 mg/kg 123.2 ± 15.3 127.0 ± 15.0 130.0 ± 14.5 136.6 ± 13.7 139.3± 4.6
150 mg/kg 123.5 ± 10.2 128.0 ± 10.4 131.5 ± 9.4 136.0 ± 9.3 141.0±10.0
300 mg/kg 122.7 ± 5.8 126.5 ± 5.5 130.0 ± 5.8 133.7 ± 6.3 137.2 ± 6.5

Groups Organ weight (g) ± SD
Liver Heart Kidneys Lungs Spleen

Control 5.72 ± 0.66 0.62 ± 0.05 1.28 ± 0.13 1.16 ± 0.11 0.78 ± 0.19
75 mg/kg 5.65 ± 0.58 0.56 ± 0.06 1.25 ± 0.06 1.09 ± 0.11 0.81 ± 0.13
150 mg/kg 5.93 ± 0.75 0.55 ± 0.05 1.33 ± 0.10 1.25 ± 0.37 0.74 ± 0.11
300 mg/kg 5.08 ± 0.37 0.54 ± 0.04 1.22 ± 0.06 1.37 ± 0.25 0.86 ± 0.44

Mice (5) were administered with 60, 120, and 240mg/kg doses of HEEF, with 75, 150, and 300mg/kg doses of HEAI for 28 days, and mean body weight and organ weight were recorded before the treatment (day 0) and on days 7, 14, 21, and 28. The control group received 200 µL of distilled water.