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. 2018 Nov 3;18:77. doi: 10.1186/s12902-018-0303-x

Table 4.

Subjects with type 2 diabetes

Subjects 1 2 3 4 5 6 7 8 9 10 11
Baseline Glucose 117 173 323 321 113 110 254 261 137 386 457
Glucose after 1 month 51 187 137 135 133 106 186 118 334 138
Glucose after 6 months 164 167 158 107 97 143 116 77
HbA1c before 8.6 10 8.8 14.6 6 6.5 12.1 6.3 8.6
HbA1c after 1 month 5.2 7.5 11 6 6.7
HbA1c after 6 months 7.1 6.2 7.6 6.3 6 5.7 7.6 5.7
Treatment before Glyburide
5 mg TID
Metformin 500 mg TID
Metformin 500 mg TID
Glyburide 5–5 – 2.5
Metformin / glyburide 500 mg/5 mg TID Glyburide 5 mg BID
Metformin 850 mg QD
Metformin 500 mg QD Metformin 500 mg QD Glyburide 5 mg TID
Metformin 850 TID
Insulin Glargine 30 U QD
Metformin 850 mg QD
Metformin / glyburide 500 mg/5 mg half dose TID NPH 45–0-20
Lispro 10–10-2
Glyburide 5 mg TID
Metformin 850 mg TID
Treatment after 6 months Stayed the same Metformin 500 mg TID
Glyburide 5 mg TID
Metformin /glyburide 500 mg/5 mg BID Stayed the same Stayed the same NPH insulin 25 U QD
Metformin 850 mg TID
Stayed the same NPH 25–0-20
Lispro 10–10-3
Suspended Metformin
Glyburide 5 mg TID

HbA1c Glycated hemoglobin, TID three times a day, BID two times a day, QD once a day, NPH neutral protamine Hagedorn