Table 5.

Studies assessing effect of imatinib on glucose metabolism of subjects with T2DM

Author	Year	N	Effect	Reference
Agostino et al.	2011	17	47% of the subjects could discontinue their medications. All the subjects had a reduction in FPG.	[2]
Breccia et al.	2004	7	85.7% of the subjects reduced FPG concentration allowing dose decrease of oral hypoglycemic agents.	[3]
Iurlo et al.a	2015	27	Improve FPG levels and reduction of the dosage of antihyperglycemic drugs.	[22]
Dingli et al. b	2007	7	There was no reduction of FG, HbA1c or antidiabetic treatment in any of the patients.	[9]

FPG fasting plasma glucose

^aIn this study, the authors did not separate subjects with IFG and T2DM

^bTwo patients of the group with normal fasting glucose developed diabetes during the treatment with imatinib