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. 2018 Nov 3;16:110. doi: 10.1186/s12958-018-0423-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — T2D mouse model has a low fecundity. (a) The litter size was significantly decreased in T2D mice compared to the T2 DC group (P<0.05). (b) T2D-F1 newborn mice had a significantly higher malformation rate and significantly decreased low (c) birth weight compared to the T2 DC group (P<0.05)