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. 2018 Nov 3;19:212. doi: 10.1186/s12931-018-0904-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Association between DNA methylation levels and gene expression of AHRR in lung tissue. a and c) DNA methylation levels are presented on the X-axis and the normalized gene expression levels are shown on the Y-axis. Blue circles = never smokers, gray squares = ex-smokers and yellow triangles = current smoker. b and d) DNA methylation levels are presented on the X-axis and the average of the normalized gene expression levels distributed per 2% DNA methylation are shown on the Y-axis. The upper part with yellow bars represents current smokers, the middle part with gray bars represents ex-smokers and the lower part with blue bars represent never smokers