Table 1.
Demographic data (means and standard deviations) and hormone values for the postmenopausal women by COMT genotype and estradiol group. One interaction was found for the Wechsler Test of Adult Reading (WTAR; (F(2,87) = 5.08, p = .008). Abbreviations: Wechsler Test of Adult Reading (WTAR), Body Mass Index (BMI), Pittsburch Sleep Quality Inventory (PSQI), Follicule Stimulating Hormone (FSH).
| Met/Met | Met/Val | Val/Val | Met/Met | Met/Val | Val/Val | |
|---|---|---|---|---|---|---|
| Low E2 | Low E2 | Low E2 | High E2 | High E2 | High E2 | |
| N=14 | N=21 | N=13 | N=9 | N=23 | N=13 | |
| Age (y) | 57.07 (2.4) | 56.00 (2.5) | 56.33 (2.3) | 55.78 (2.5) | 56.17 (3.1) | 55.88 (2.3) |
| Years since Menopause (y) | 5.69 (2.8) | 7.14 (5.2) | 4.57 (3.5) | 5.67(4.3) | 6.26 (4.9) | 5.69 (2.5) |
| Education (y) | 15.57 (2.5) | 16.67 (2.6) | 16.77 (1.9) | 15.11 (1.8) | 15.74 (2.45) | 16.31 (2.4) |
| WTAR (IQ)* | 121.21 | 116.14 | 117.85 | 111.33 | 117.70 | 118.46 |
| (4.6) | (8.9) | (5.8) | (8.5) | (6.9) | (6.7) | |
| BMI (kg/m2) | 27.07 (5.7) | 25.07 (4.1) | 24.60 (3.6) | 27.82 (4.5) | 24.67 (4.1) | 26.65 (4.9) |
| PSQI (Total) | 4.57 (2.3) | 5.62 (3.6) | 5.46 (3.5) | 4.44 (3.1) | 6.04 (3.2) | 4.08 (3.5) |
| FSH (IU/ml) | 75.4 (20.4) | 75.22 (17.6) | 94.45 (23.7) | 76.60 (28.0) | 85.91 (26.9) | 77.95 (21.9) |
| Estradiol(pg/ml) | 4.34 (1.1) | 3.50 (1.1) | 4.08 (1.0) | 14.90 (6.3) | 14.36 (5.8) | 11.37 (5.2) |
| Range | 4.08 | 3.40 | 2.86 | 18.14 | 18.93 | 15.05 |
| Estrone (pg/ml) | 40.43 (9.4) | 34.27 (9.8) | 34.74 (7.6) | 37.81 (12.8) | 31.97 (14.3) | 31.14 (13.6) |
| Range | 33.34 | 35.30 | 26.96 | 32.38 | 66.66 | 45.84 |
*
interaction of COMT and estradiol group (F(2,87) = 5.08, p = .008)