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Aβ42 and Aβ40 peptide levels were measured in brain homogenates from the A) cortex and B) hippocampus of APP/PS1 (n = 7) and APP/PS1 + HU (n = 8) mice in cohort 1. There were no significant differences between Aβ42 and Aβ40 levels in the cortical (p ≥ 0.224) or hippocampal (p ≥ 0.063) samples or between the ratio of Aβ42 /Aβ40 (C; p ≥ 0.415) in the cortical or hippocampal samples.
