| Outcome | Model | AUC (95%CI) | PRC |
|---|---|---|---|
| Prevalent KP | Full | 0.76 (0.74; 0.77) | 100% |
| without central | 0.71 (0.70; 0.72) | 19% | |
| without peripheral | 0.70 (0.69; 0.71) | 23% | |
| without others | 0.69 (0.67; 0.70) | 27% | |
| Incident KP | Full∗ | 0.71 (0.68; 0.75) | 100% |
| without central | 0.68 (0.64; 0.72) | 14% | |
| without peripheral | 0.65 (0.62; 0.69) | 29% | |
| without others | 0.68 (0.64; 0.72) | 14% | |
| Worsening KP | Full∗ | 0.71 (0.68; 0.73) | 100% |
| without central | 0.65 (0.62; 0.68) | 29% | |
| without peripheral | 0.70 (0.67; 0.73) | 5% | |
| without others | 0.68 (0.65; 0.71) | 14% |
Risk factors included in the full model:
• Central: Widespread pain; HADS - Hospital Anxiety and Depression Scales; PCS - Pain Catastrophizing Scale.
• Peripheral: History of significant injury; early life mal-alignment; current mal-alignment; high risk occupation.
• Others: Age; gender; BMI; number of comorbidities; nodal hand osteoarthritis.
Abbreviations: AUC – area under the curve; CI –confidence interval. PRC – proportional risk contribution.
∗
New knee injury (past 12 months) as an additional peripheral risk factor was included in analysis.