Table 2.
Telomere length | NFPA (N = 114) | Controls (N = 106) | ||||
---|---|---|---|---|---|---|
β | P | N | β | P | N | |
Age | 0.17* | <0.001* | 114* | 0.08* | 0.003* | 106* |
BMI | 0.017 | 0.167 | 114 | 0.012 | 0.092 | 106 |
Gender | 0.000 | 0.896 | 114 | 0.005 | 0.467 | 106 |
Current smoking status | 0.003 | 0.556 | 104 | 0.001 | 0.739 | 100 |
Diabetes mellitus type 2 | 0.040* | 0.032* | 114* | 0.015 | 0.232 | 104 |
Fasting glucose | 0.020 | 0.13 | 99 | NA | NA | NA |
HbA1c | 0.051* | 0.04* | 83* | NA | NA | NA |
Arterial hypertension | 0.120* | <0.001* | 114* | 0.000 | 0.965 | 104 |
Number of antihypertensive drugs | 0.130* | <0.001* | 114* | NA | NA | NA |
Systolic blood pressure | 0.060* | 0.009* | 107* | NA | NA | NA |
Diastolic blood pressure | 0.006 | 0.424 | 107 | NA | NA | NA |
Waist-to-hip ratio | 0.017 | 0.294 | 66 | NA | NA | NA |
Waist circumference | 0.030* | 0.09* | 84* | NA | NA | NA |
Total leukocyte count | 0.050* | 0.03* | 107* | NA | NA | NA |
Time since diagnosis | 0.017 | 0.255 | 79 | NA | NA | NA |
Pituitary insufficiency of any axis | 0.014 | 0.202 | 114 | NA | NA | NA |
Overt sex steroid deficiency | 0.012* | 0.178* | 114* | NA | NA | NA |
Hypothyroidism | 0.005 | 0.472 | 114 | NA | NA | NA |
Overt growth hormone deficiency | 0.006 | 0.412 | 114 | NA | NA | NA |
Growth hormone dose | 0.020 | 0.368 | 36 | NA | NA | NA |
IGF-1-SDS | 0.004 | 0.526 | 99 | NA | NA | NA |
Adrenal insufficiency | 0.001 | 0.731 | 114 | NA | NA | NA |
Daily total hydrocortisone dose | 0.060* | 0.091* | 52* | NA | NA | NA |
Diabetes insipidus | 0.003 | 0.551 | 114 | NA | NA | NA |
Triglycerides | 0.008 | 0.395 | 97 | NA | NA | NA |
Current statin use | 0.030* | 0.079* | 114* | NA | NA | NA |
Total cholesterol | 0.007 | 0.388 | 109 | NA | NA | NA |
HDL cholesterol | 0.003 | 0.580 | 94 | NA | NA | NA |
LDL cholesterol | 0.002 | 0.662 | 93 | NA | NA | NA |
*Parameters which showed a linear correlation at least on trend level (P < 0.1) with telomere length.