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. 2018 Oct 29;8:476. doi: 10.3389/fonc.2018.00476

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Copyright © 2018 Pedra, Galdino, da Silva, Ramos, Bona, Soares, Azambuja, Canuto, de Brito, Ribeiro, Souza, Cunico, Stefanello, Spanevello and Braganhol.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparative effect of eDCM and eEtAc on glioma cell proliferation. C6 (left panel) and U87MG (right panel) glioma cell lines were exposed to increasing concentrations of eDCM (A,B) and eEtAc (C,D). Cell proliferation was determined by SRB assay following 24, 48, or 72 h of treatment, as indicated. Values represent the mean ± SEM from at least three independent experiments performed in triplicate. Data were analyzed by ANOVA followed by post-hoc comparisons (Tukey test). *, **, *** Significantly different from control cells (P < 0.05, P < 0.01, and P < 0.001, respectively).