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. 2018 Sep 25;109(11):3564–3574. doi: 10.1111/cas.13776

Figure 4.

Figure 4

Knockdown of androgen receptor (AR) or blocking AR signaling reduces migration and invasion of C4‐2B cells. A, Knockdown of AR with siRNA reduced migration and invasion of C4‐2B cells as determined by Transwell assay. Images of Transwell migration assay and Transwell invasion assay as well as western blotting confirming the knockdown of AR are shown in (B) and (C), respectively. D, Treating C4‐2B cells with 5 μmol/L Casodex (bicalutamide) reduced cell migration as determined by Transwell assay. Asterisk represents statistical significance < 0.05 between the two groups being compared