Table 1.
Relationship between milk fat globule‐epidermal growth factor factor 8 (MFG‐E8) expression and clinicopathological factors in 134 patients with esophageal squamous cell carcinoma
| Patient characteristics | Total | MFG‐E8 low | MFG‐E8 high | P‐value | |
|---|---|---|---|---|---|
| n = 134 (%) | n = 102 (%) | n = 32 (%) | |||
| Age, years | ≤65 | 73 (54.5) | 52 (38.8) | 21 (15.7) | .15 |
| >65 | 61 (45.5) | 50 (37.3) | 11 (8.2) | ||
| Sex | Male | 117 (87.3) | 86 (64.2) | 31 (23.1) | .06 |
| Female | 17 (12.7) | 16 (11.9) | 1 (0.8) | ||
| Location[Link] | Ut | 18 (13.4) | 10 (7.5) | 8 (6.0) | .028 |
| Mt‐Lt | 116 (86.6) | 92 (68.7) | 24 (17.9) | ||
| Tumor differentiation[Link] | Well‐Mod | 102 (76.1) | 81 (60.5) | 21 (15.7) | .11 |
| Por | 32 (23.9) | 21 (15.7) | 11 (8.2) | ||
| Neoadjuvant chemotherapy | With | 68 (50.7) | 41 (30.6) | 27 (20.2) | <.0001 |
| Without | 66 (49.3) | 61 (45.5) | 5 (3.7) | ||
| Tumor depth[Link] | pT1‐2 | 47 (35.1) | 37 (27.6) | 10 (7.5) | .6000 |
| pT3‐4 | 87 (64.9) | 65 (48.5) | 22 (16.4) | ||
| Lymph node metastasis[Link] | pN0‐1 | 83 (61.9) | 69 (51.5) | 14 (10.5) | .0150 |
| pN2‐3 | 51 (38.1) | 33 (24.6) | 18 (13.4) | ||
| Non‐regional lymph node metastasis[Link] | pM0 | 111 (82.8) | 91 (67.9) | 20 (14.9) | .0005 |
| pM1 | 23 (17.2) | 11 (8.2) | 12 (9.0) | ||
| Tumor stage[Link] | I‐II | 51 (38.0) | 42 (31.3) | 9 (6.7) | .1800 |
| III‐IV | 83 (62.0) | 60 (44.8) | 23 (17.2) | ||
Upper (Ut), middle (Mt), and lower (Lt) third of thorax.
Well, moderately (Mod), and poorly (Por) differentiated squamous cell carcinoma.
Pathological classification according to UICC (7th edition).