Table 2.
Difference in clinical and pathological characteristics of patients with esophageal squamous cell carcinoma treated with or without neoadjuvant chemotherapy (NAC)
| Patient characteristics | Total | NAC− | NAC+ | P‐value | |
|---|---|---|---|---|---|
| n = 134 (%) | n = 66 (%) | n = 68 (%) | |||
| Age, years | ≤65 | 73 (54.5) | 30 (22.4) | 43 (32.1) | .0390 |
| >65 | 61 (45.5) | 36 (26.9) | 25 (18.7) | ||
| Sex | Male | 117 (87.3) | 57 (42.5) | 60 (44.8) | .7400 |
| Female | 17 (12.7) | 9 (6.7) | 8 (6.0) | ||
| Location[Link] | Ut | 18 (13.4) | 12 (9.0) | 6 (4.5) | .1100 |
| Mt‐Lt | 116 (86.6) | 54 (40.3) | 62 (46.3) | ||
| Tumor differentiation[Link] | Well‐Mod | 102 (76.1) | 52 (38.8) | 50 (37.3) | .4800 |
| Por | 32 (23.9) | 14 (10.5) | 18 (13.4) | ||
| cT[Link] | cT1‐2 | 57 (42.5) | 37 (27.6) | 20 (14.9) | .0018 |
| cT3‐4 | 77 (57.5) | 29 (21.6) | 48 (35.8) | ||
| cN[Link] | cN0 | 42 (31.3) | 36 (26.9) | 6 (4.5) | <.0001 |
| cN1 | 92 (68.7) | 30 (22.4) | 62 (46.3) | ||
| cM[Link] | cM0 | 107 (79.9) | 62 (46.3) | 45 (33.6) | <.0001 |
| cM1 | 27 (20.2) | 4 (3.0) | 23 (17.2) | ||
| cStage[Link] | cI‐II | 51 (38.1) | 39 (29.1) | 12 (9.0) | <.0001 |
| cIII‐IV | 83 (61.9) | 27 (20.2) | 56 (41.8) | ||
| pT[Link] | pT1‐2 | 47 (35.1) | 28 (20.9) | 19 (14.2) | .0800 |
| pT3‐4 | 87 (64.9) | 38 (28.4) | 49 (36.6) | ||
| pN[Link] | pN0‐1 | 42 (31.3) | 41 (30.6) | 83 (61.9) | .6900 |
| pN2‐3 | 24 (17.9) | 27 (20.2) | 51 (38.1) | ||
| pM[Link] | pM0 | 111 (82.8) | 61 (45.5) | 50 (37.3) | .0037 |
| pM1 | 23 (17.2) | 5 (3.7) | 18 (13.4) | ||
| pStage[Link] | pI‐II | 51 (38.1) | 30 (22.4) | 21 (15.7) | 0.0800 |
| pIII‐IV | 83 (61.9) | 36 (26.9) | 47 (35.1) | ||
Upper (Ut), middle (Mt), and lower (Lt) third of thorax.
Well, moderately (Mod), and poorly (Por) differentiated squamous cell carcinoma.
Clinical classification of tumor depth (cT), lymph node metastasis (cN), non‐regional lymph node metastasis (cM), and stage (cStage) in UICC (6th edition).
Pathological classification of tumor depth (pT), lymph node metastasis (pN), non‐regional lymph node metastasis (pM), and stage (pStage) in UICC (7th edition).