Table 1.

Functional characterization of human adrenocortical carcinoma samples (n = 13) towards their GNRHR, LHCGR, FSHR mRNA and protein expression, proliferation and hormone secretion.

Patient number	Sex	Age	Stage (ENSAT)	Size (cm)	Hormone secretion	MKI67 (%)	GNRHR/GNRHR	LHCGR/LHCGR	FSHR/FSHR
1	Male	46	2	9.5	Aldosterone	20	+	+	−
2	Female	60	2	13	Androgen	20	+	+	−
3	Female	30	4	17	Androgen	40	+	+	−
4	Female	72	4	8	Cortisol	20	−	−	−
5	Female	57	4	12	Cortisol + androgens	20	+	+	−
6	Male	31	2	11	No clinical evidence	2	−	+	−
7	Female	40	2	21.5	No clinical evidence	10	−	−	−
8	Male	50	2	20	No clinical evidence	7	+	+	−
9	Female	46	3	18	No clinical evidence	40	−	+	−
10	Male	44	4	13	No clinical evidence	10	−	−	−
11	Female	44	4	4.5	Slight cortisol	50	+	+	−
12	Male	64	4	16	Slight cortisol	10	−	+	−
13	Male	59	4	5.5	Slight cortisol + androgen precursors	10	+	+	−