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. 2018 Sep 24;239(3):389–402. doi: 10.1530/JOE-18-0316

Table 3.

UTL and supplemental vitamin A diets did not affect trabecular bone.

Tibia Vertebra
Tb.BMD BV/TV Tb.N Tb.Th Tb.Sp
4 weeks (n = 15/group) (n = 10/group)
 Control 209 ± 6 22.8 ± 1.1 4.96 ± 0.2 46 ± 1 93 ± 3
 UTL 211 ± 6 (−20.7, 24.6)
 Supplemented 219 ± 9 (−12.1, 33.2) 23.3 ± 1.2 (−2.91, 3.75) 5.22 ± 0.2 (−0.33, 0.85) 45 ± 1 (−4.02, 0.96) 96 ± 4 (−7.94, 13.4)
10 weeks (n = 10/group) (n = 10/group)
 Control 200 ± 8 22.1 ± 1.0 4.77 ± 0.2 47 ± 0.7 158 ± 4
 UTL 210 ± 12 (−26.3, 45.0)
 Supplemented 179 ± 12 (−56.5, 14.8) 22.4 ± 1.4 (−3.37, 3.79) 5.02 ± 0.3 (−0.53, 1.04) 45 ± 1 (−4.54, 0.43) 155 ± 5 (−16.2, 10.2)

Trabecular bone mineral density (Tb. BMD; mg/cm3), as analyzed by pQCT, in tibia at 4 and 10 weeks of UTL and supplemented vitamin A diet. Vertebral bone volume/tissue volume (BV/TV; %), trabecular number (Tb.N; /mm), thickness (Tb.Th; µm) and separation (Tb.Sp; µm) of the L5 vertebra via µCT after 4 and 10 weeks of supplemented vitamin A treatment and the 95% CI of the effect in brackets. Values are given as mean ± s.e.m. 1-way ANOVA followed by Dunnett’s multiple comparison test vs control for tibia pQCT and Student’s t-test vs control for µCT of vertebra.