Table 3.
UTL and supplemental vitamin A diets did not affect trabecular bone.
| Tibia | Vertebra | ||||
|---|---|---|---|---|---|
| Tb.BMD | BV/TV | Tb.N | Tb.Th | Tb.Sp | |
| 4 weeks | (n = 15/group) | (n = 10/group) | |||
| Control | 209 ± 6 | 22.8 ± 1.1 | 4.96 ± 0.2 | 46 ± 1 | 93 ± 3 |
| UTL | 211 ± 6 (−20.7, 24.6) | – | – | – | – |
| Supplemented | 219 ± 9 (−12.1, 33.2) | 23.3 ± 1.2 (−2.91, 3.75) | 5.22 ± 0.2 (−0.33, 0.85) | 45 ± 1 (−4.02, 0.96) | 96 ± 4 (−7.94, 13.4) |
| 10 weeks | (n = 10/group) | (n = 10/group) | |||
| Control | 200 ± 8 | 22.1 ± 1.0 | 4.77 ± 0.2 | 47 ± 0.7 | 158 ± 4 |
| UTL | 210 ± 12 (−26.3, 45.0) | – | – | – | – |
| Supplemented | 179 ± 12 (−56.5, 14.8) | 22.4 ± 1.4 (−3.37, 3.79) | 5.02 ± 0.3 (−0.53, 1.04) | 45 ± 1 (−4.54, 0.43) | 155 ± 5 (−16.2, 10.2) |
Trabecular bone mineral density (Tb. BMD; mg/cm3), as analyzed by pQCT, in tibia at 4 and 10 weeks of UTL and supplemented vitamin A diet. Vertebral bone volume/tissue volume (BV/TV; %), trabecular number (Tb.N; /mm), thickness (Tb.Th; µm) and separation (Tb.Sp; µm) of the L5 vertebra via µCT after 4 and 10 weeks of supplemented vitamin A treatment and the 95% CI of the effect in brackets. Values are given as mean ± s.e.m. 1-way ANOVA followed by Dunnett’s multiple comparison test vs control for tibia pQCT and Student’s t-test vs control for µCT of vertebra.
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