Table 4.

Expression analysis of osteoclastic and osteoblastic genes in cortical bone after 4 and 10 weeks of supplemented vitamin A diet.

	4 week		CI of effect	10 week		CI of effect
	Control	Supplemented		Control	Supplemented
Acp5 (Trap)	1.00 ± 0.16	0.78 ± 0.07	−0.58, 0.14	1.00 ± 0.10	0.89 ± 0.08	−0.38, 0.17
Ctsk	1.00 ± 0.17	0.81 ± 0.08	−0.59, 0.21	1.00 ± 0.11	0.83 ± 0.06	−0.44, 0.09
Tnfrsf11a (Rank)	1.00 ± 0.12	0.97 ± 0.09	−0.35, 0.29	1.00 ± 0.10	0.90 ± 0.05	−0.34, 0.14
Tnfsf11 (Rankl)	1.00 ± 0.17	0.90 ± 0.07	−0.49, 0.29	1.00 ± 0.13	1.03 ± 0.13	−0.35, 0.42
Tnfrsf11b (Opg)	1.00 ± 0.20	0.79 ± 0.12	−0.69, 0.27	1.00 ± 0.06	1.39 ± 0.19	−0.03, 0.82
Bglap (Ocn)	1.00 ± 0.18	0.49 ± 0.08*	−0.93, −0.09	1.00 ± 0.10	1.05 ± 0.18	−0.37, 0.48
Alpl	1.00 ± 0.15	0.63 ± 0.06*	−0.70, −0.04	1.00 ± 0.07	1.13 ± 0.17	−0.25, 0.51
Col1α1	1.00 ± 0.17	0.82 ± 0.07	−0.57, 0.21	1.00 ± 0.10	1.10 ± 0.17	−0.31, 0.52
Runx2	1.00 ± 0.20	0.60 ± 0.07	−0.84, 0.04	1.00 ± 0.07	1.06 ± 0.06	−0.14, 0.25
Sp7 (Osterix)	1.00 ± 0.13	1.35 ± 0.20	−0.14, 0.85	1.00 ± 0.06	1.18 ± 0.11	−0.09, 0.45

Osteoclastic (Acp5, Ctsk, Tnfrsf11a, Tnfsf11, and Tnfrsf11b) and osteoblastic (Bglap, Alpl, Col1α1, Runx2, and Sp7) genes at 4 and 10 weeks of supplemented vitamin A treatment and the 95% CI of the effect. Data is displayed as fold change relative to control, n = 10/group, mean ± s.e.m., Student’s t-test vs control.

*P < 0.05.