Table 3.
Multivariate analysis for maternal characteristics and laboratory data according to fetal macrosomia outcomes
| Covariates | No. participants | No. events | Odds ratio (95% CI) | P‐value† |
|---|---|---|---|---|
| Overall | 793 | 51 | ||
| Age (years) | ||||
| <25 | 187 | 9 | ||
| 25–29.99 | 391 | 21 | 0.876 (0.378–2.026) | 0.756 |
| 30–34.99 | 161 | 17 | 1.431 (0.561–3.652) | 0.453 |
| ≥35 | 54 | 4 | 0.952 (0.246–3.688) | 0.943 |
| Menarche age (years) | ||||
| <13 | 48 | 1 | ||
| 13–14 | 571 | 43 | 2.866 (0.376–21.832) | 0.310 |
| >14 | 174 | 7 | 1.287 (0.148–11.185) | 0.819 |
| History of cesarean section | ||||
| No | 641 | 36 | ||
| Yes | 152 | 15 | 1.046 (0.490–2.232) | 0.908 |
| History of miscarriage | ||||
| No | 732 | 44 | ||
| Yes | 61 | 7 | 1.552 (0.624–3.860) | 0.345 |
| History of induced abortion | ||||
| No | 445 | 26 | ||
| Yes | 348 | 25 | 0.998 (0.529–1.884) | 0.996 |
| History of premature delivery | ||||
| No | 787 | 51 | ||
| Yes | 6 | 0 | 0.000 | 0.999 |
| Pre‐pregnancy BMI (kg/m2) (kg/m2) | ||||
| <18.50 | 102 | 1 | ||
| 18.50–23.99 | 507 | 24 | 5.986 (0.774–46.270) | 0.086 |
| 24.00–27.99 | 158 | 21 | 15.734 (1.984–124.796) | 0.009* |
| ≥28 | 26 | 5 | 26.257 (2.695–255.796) | 0.005* |
| Serum ferritin (ng/mL) | ||||
| <30 | 542 | 30 | ||
| 30–70 | 207 | 13 | 0.946 (0.465–1.928) | 0.879 |
| >70 | 44 | 8 | 3.191 (1.247–8.167) | 0.016* |
| FPG × PG(1 h) × PG(2 h) (mmol/L) | ||||
| normal | 775 | 45 | ||
| Abnormal | 18 | 6 | 5.322 (1.663–17.034) | 0.005* |
*P < 0.05 vs body mass index <18.5, vs serum ferritin <30 ng/mL and vs FPG × PG (1 h) × PG (2 h) normal, factors significantly associated with macrosomia. †Binary logistic regression. 1 h‐PG, plasma glucose 1 h after the oral glucose tolerance test; 2 h‐PG, plasma glucose 2 h after the oral glucose tolerance test; FPG, fasting plasma glucose; FPG × PG (1 h) × PG (2 h), the interaction of plasma glucose at different periods.