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. 2018 Nov 1;20(12):1187–1197. doi: 10.1016/j.neo.2018.10.002

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© 2018 Published by Elsevier Inc. on behalf of Neoplasia Press, Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Immunocytochemical staining of PCNA, p-ErK, p-Akt, and E-cadherin in sections of normal intestine from wild-type fish and tubular adenoma from kras+ transgenic zebrafish. (A and B) Immunostaining of PCNA (A) and quantification of percentages of positive cells (B). (C and D) Immunostaining of p-Erk (C) and quantification of percentages of positive cells (D). (E and F) Immunostaining of p-Art (E) and quantification of percentages of positive cells (F). (G and H) Immunostaining of E-cadherin (G) and quantification of percentages of positive cells (H). Numbers of samples from each group are indicated in the quantification histograms. Statistical significance: ***P < .001.