Table 2.
Cortical thickness and cortical thinning rate by biomarker abnormality classifications
| Cortical thickness | Cortical thinning rate | |
|---|---|---|
| Biomarker abnormality profile | BLOW Amyloid, LOW WMH = 2.73 [2.58, 2.88] BLOW Amyloid, HIGH WMH = 2.61 [2.58, 2.64] BHIGH Amyloid, LOW WMH = 2.47 [2.38, 2.57]* BHIGH Amyloid, HIGH WMH = 2.51 [2.49, 2.54]* |
BLOW Amyloid, LOW WMH = −0.002 [−0.016, 0.013] BLOW Amyloid, HIGH WMH = −0.008 [−0.012, −0.003]** BHIGH Amyloid, LOW WMH = −0.002 [−0.011, 0.008] BHIGH Amyloid, HIGH WMH = −0.008 [−0.012, −0.005]** |
| Age | B = −0.028 [−0.036, −0.019] P < .001 | B = 8.1E-5 [−0.003, 0.003] P = .96 |
| Sex | BM = −0.016 [−0.065, 0.034] P = .53 | BM = 0.007 [−0.014, 0.029] P = .50 |
| APOE4 | BE4+ = −0.009 [−0.054, 0.037] P = .70 | BE4+ = −0.011 [−0.032, 0.009] P = .27 |
| Education | B = 0.008 [−0.0003, 0.015] P = .059 | B = 0.004 [0.0003, 0.007] P = .03 |
| Intracranial total volume | B = 8.1E-8 [−7.8E-8, 2.4E-7] P = .32 | B = 1.3E-8 [-5.5E-8, 8.1E−8] P = .71 |
* Denotes significant difference from reference group (low amyloid, low WMH). ** Denotes significant difference from 0.
NOTE. Values are presented as mean parameter estimate [95% CI] and bolded if P < .05. Rows represent all the variables included in a single linear mixed effects or growth curve model (column).