Table 3.

Correlation between tracers and CDR-SB

Region	FDG and CDR-SB		PiB-R1 and CDR-SB		ePiB and CDR-SB
	rho	P value	rho	P value	rho	P value
Precuneus	−0.45	.0001	−0.27	.029	0.17	.182
Inferior Parietal	−0.47	<.0001	−0.28	.026	0.06	.650
Superior Parietal	−0.47	<.0001	−0.44	.0002	−0.04	.781
Lateral Occipital	−0.26	.034	−0.17	.188	0.20	.103
Hippocampus	−0.30	.014	−0.22	.084	−0.21	.095

Abbreviations: CDR-SB, Clinical Dementia Rating–Sum of Boxes; FDG, ¹⁸F-fluorodeoxyglucose; PiB, ¹¹C-Pittsburgh compound B; EPiB, early frames of the PiB scan.

NOTE. Statistically significant values are listed in bold (P value <.05).

NOTE. Evaluation of correlation between the tracers and dementia in mutation carriers (n = 65). Spearman's rank correlation coefficient (rho) and P values are displayed for FDG and CDR-SB, ePiB, and CDR-SB, and for PiB-R1 and CDR-SB. There were strong negative correlations between FDG and CDR-SB, but no correlation between ePiB and CDR-SB.