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. 2018 Oct 1;9(20):3787–3796. doi: 10.7150/jca.26275

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Fig 1 — Loss of BAP1 is associated with renal cell carcinoma and prognosis. (A) Mutation frequency and types of BAP1 in clear cell renal cell carcinoma (ccRCC) reproduced from the cancer Genome Atlas (TCGA) database; (B) correlation between BAP methylation and mRNA expression; and B) relation between BAP1 copy number change and mRNA expression; Data from (C) HPA (left) and GDS2880 (right) and (D) ONCOMINE showing that mRNA level of BAP1 is significantly downregulated in human ccRCC. Representative immunohistochemistry (IHC) of BAP1 on benign renal and ccRCC tissues; (E) Overall survival between cases with higher or lower BAP1 expression in ccRCC and pRCC reproduced from TCGA database.