Fig 2.

EZH 2 was upregulated in ccRCC with low BAP1 level. (A) Functional annotation and pathway analysis of enriched genes in BAP1 mutated ccRCC compared with pan-negative cases, reproduced from the cancer Genome Atlas (TCGA) database, showing 14 significantly changed pathways; (B) Correlation between expressions of BAP1 and EZH2 in TCGA-KIRC database; (C) Overall survival between cases with higher or lower EZH2 expression in ccRCC reproduced from TCGA database; (D) Reproduced from HPA, showing typical EZH1 positive cells in IHC.