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Expression of EZH2 was higher in BAP1-mutant ccRCC cell line. (A) Efficacy of lentiviral delivery of BAP1 overexpression in 769-P ccRCC cells; (B) Efficacy of shRNA against BAP1 in 786-O ccRCC cells; (C) Protein levels of BAP1, EZH2, H3K27me3 in 769-P and 786-O cells with genetic manipulation of BAP1 status (**P < 0.01).
