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. 2018 Oct 3;14(12):1732–1744. doi: 10.7150/ijbs.24232

Figure 3.

Figure 3

The inflammatory targets of NF-κB were activated in p65-overexpressing cells. The heat maps of the consistently altered genes in p65-overexpressing and knockdown cells are shown. The RNA from SW982 cells, SW982 cells overexpressing p65 (S-OE), SW982 cells with knockdown of p65 (S-KD), HFLS-RA cells (HFLS), HFLS-RA cells overexpressing p65 (H-OE), and HFLS-RA cells with knockdown of p65 (H-KD) were subjected to microarray analysis. The elevated genes are indicated in red, and the downregulated genes are shown in green. qRT-PCR was performed to verify the expression of TNF-α (B), IL-6 (C), COX-2 (D), IRF-1 (E), CCL5 (F), and CCL20 (G) in SW982, S-OE, S-KD, HFLS, H-OE and H-KD cells. * P <0.05; ** P < 0.001; *** P <0.0001.