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. 2018 Oct 3;14(12):1732–1744. doi: 10.7150/ijbs.24232

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miR-7-5p was significantly downregulated in RA patients. (A) The heat maps of the consistently altered miRNAs in RA patients are shown. RNA samples from three paired joint tissue specimens (HC-4, -5, -6 and RA-4, 5, -6) were subjected to miRNA microarray analysis. The elevated miRNAs are indicated in red, and the downregulated miRNAs are shown in green. qRT-PCR was performed to verify the expression of miR-7-5p (B), miR-124a (C), miR-338 (D), miR-568 (E), miR-575 (F), miR-148b (G), miR-177 (H), miR-198 (I) and miR-600 (J) in the RNA samples used in A. * P <0.05; ** P < 0.001.