Table 3.
Phenotypic features and status of SHOX2 mutation of the affected living pedigree members.
| Subject information | Phenotype | Electrocardiogram | Echocardiogram | Genotype | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Identity | Gender | Age at time of study (years) | Age at diagnosis of AF (years) | AF (Classification) | Heart rate (beats/min) | QRS interval (ms) | QTc | LAD (mm) | LVEF (%) | SHOX2 mutation |
| Family 1 | R194X | |||||||||
| II-1 | M | 53 | 41 | Permanent | 87 | 100 | 447 | 35 | 62 | +/- |
| II-6 | F | 47 | 43 | Permanent | 62 | 116 | 528 | 38 | 60 | +/- |
| II-7 | M | 45 | 39 | Persistent | 71 | 102 | 450 | 33 | 63 | +/- |
| III-1 | F | 20 | 20 | Paroxysmal | 75 | 96 | 435 | 30 | 65 | +/- |
AF: atrial fibrillation, F: female, M: male, QTc: corrected QT interval, LAD: left atrial diameter, LVEF: left ventricular ejection fraction, +/-: heterozygote.