Table 2.

CGP-37157 enhances the Rhod 2- or MitoSOX-red-fluorescence responses mediated by arsenite.

Treatment	Rhod 2-fluorescence (arbitrary units)	MitoSOX red-fluorescence (arbitrary units)
Untreated RP-cells	11.5 ± 1.4	11.3 ± 1.1
CGP-37157	16.9 ± 1.2	11.8 ± 1.3
Arsenite	20.4 ± 2.2	15.1 ± 1.5
Arsenite + CGP-37157	36.4 ± 2.4*	31.8 ± 2.6*

RP-cells were exposed for 4 h to arsenite (2.5 µM) in the absence or presence of CGP-37157 (3 µM). After treatments, the cells were analyzed for Rhod 2- or MitoSOX red-fluorescence. Results represent the means ± SD calculated from 3 separate experiments.

^*P < 0.01, as compared to cells treated with arsenite (one-way ANOVA followed by Dunnett's test).