Table 2.
Cardiac Cine-MRI Analysis of 21-Week-Old D2/mdx Mice Administered AAV-μ-Utro Compared to Vehicle Control Mice
| Systolic | Untreated | AAV-μ-Utro |
|---|---|---|
| Left Ventricle | ||
| End diastolic volume (μL) | 57.03 ± 3.27 | 46.70 ± 4.22 |
| End systolic volume (μL) | 7.43 ± 1.26 | 10.51 ± 1.76 |
| Right Ventricle | ||
| End diastolic volume (μL) | 53.45 ± 9.73 | 52.60 ± 9.06 |
| End systolic volume (μL) | 12.14 ± 2.77 | 17.16 ± 3.51 |
| Stroke volume (μL) | 41.32 ± 7.66 | 35.44 ± 6.70 |
| Diastolic | ||
| Peak ejection rate | −605.50 ± 57.60 | −412.76 ± 105.32 |
| Peak filling rate (mL/s) | 474.80 ± 60.21 | 448.72 ± 25.59 |
| Time to peak ejection rate (mL/s) | 8.50 ± 2.35 | 12.33 ± 4.24 |
Data represented as SEM, n = 8/group.