Table 1.

Clinical characteristics of subjects with amnestic mild cognitive impairment (aMCI) and healthy control (HC).

	Baseline			Follow-up
	HC	aMCI	p-value	HC	aMCI	p-value
Age (yrs)	67.25 ± 7.50	66.95 ± 9.65	0.91	68.67 ± 7.54	68.10 ± 9.67	0.84
Gender (m/f)	10/10	7/13	0.34	10/10	7/13	0.34
Education (yrs)	11.90 ± 3.82	9.65 ± 4.06	0.08	11.90 ± 3.82	9.65 ± 4.06	0.08
Volume of Lt. HP	0.562 ± 0.016	0.538 ± 0.026	0.002	0.560 ± 0.017	0.534 ± 0.027†	0.001
Volume of Rt. HP	0.538 ± 0.016	0.521 ± 0.027	0.020	0.535 ± 0.016†	0.516 ± 0.029†	0.013
CDR-SB	0 (20)	0.5 (20)	<0.001	0 (20)	0.5 (18)/1 (2)	<0.001
MMSE	28.60 ± 1.23	24.80 ± 3.70	<0.001	28.35 ± 1.46	23.45 ± 3.47†	<0.001
MoCA	26.40 ± 1.63	20.85 ± 4.70	<0.001	26.50 ± 1.87	19.50 ± 4.91†	<0.001
AVLT-immediate recall	8.88 ± 1.63	6.00 ± 1.45	<0.001	8.95 ± 1.25	6.08 ± 1.38	<0.001
AVLT-delayed recall	9.35 ± 3.54	4.55 ± 2.78	<0.001	9.25 ± 3.56	4.90 ± 3.02	<0.001
AVLT-recognition	11.25 ± 3.05	8.45 ± 3.36	<0.001	11.70 ± 2.22	7.75 ± 3.24	<0.001

Values represent means ± SD; Lt., left; Rt., right; HP, hippocampus; CDR-SB, clinical dementia rate-sum of the boxes; MMSE, mini mental state examination; MoCA, Montreal Cognitive Assessment; AVLT, auditory verbal learning test; p-values were derived from Student t-tests comparing the two groups, except for “gender” where the p-value was obtained using the χ²-test; ^†represents significant decline in follow-up vs. baseline.