Table 2.
Longitudinal changes in functional connectivity to the cornu ammonis subregions in aMCI subjects as compared to HC.
| Seed regions | Region | Cluster size (voxel) | MNI (x y z) | F/T-value | ||
|---|---|---|---|---|---|---|
| CA1R | HC vs. aMCI: [(HC1 + HC2) > (aMCI1 + aMCI2)] | |||||
| Lt. PCC | 190 | −6 | −46 | 36 | 12.67∗ | |
| Rt. MTG | 74 | 60 | −48 | 8 | 16.01∗ | |
| Baseline vs. Follow-up: [(aMCI1 + HC1) > (aMCI2 + HC2)] | ||||||
| Rt. MTG | 114 | 64 | −48 | 8 | 24.40∗ | |
| [(aMCI1 > aMCI2) > (HC1 > HC2)] | ||||||
| Rt. MTG | 108 | 64 | −48 | 8 | 5.51 | |
| CA2L | Baseline vs. Follow-up: [(aMCI1 + HC1) > (aMCI2 + HC2)] | |||||
| Bi. CC | 66 | −2 | −76 | 24 | 18.95∗ | |
| [(aMCI1 > aMCI2) > (HC1 > HC2)] | ||||||
| Bi. CC | 125 | 0 | −78 | 24 | 5.26 | |
Between-group results were thresholded at cluster-level p < 0.05 (FWE corrected); MNI, Montreal Neurological Institute; CA1R, the right cornu ammonis 1; CA2L, the left cornu ammonis 2; Lt., left; Rt., right; Bi., bilateral; PCC, posterior cingulate cortex; MTG, middle temporal gyrus; CC, cuneal cortex; ∗represents F-value.